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Phentermine is an anti-obesity agent that is supposed to be combined with a healthy diet and active lifestyle to provide for maximum efficiency. An allergic reaction to phentermine in the past may prevent you from safely taking this drug as the same reaction is most likely to occur. Before you start the treatment some tests may be required to find out if any health conditions you have or other factors may prevent you from safely taking this medicine. Make sure your health care provider knows about any health issues you have or used to have to make sure the treatment is as efficient as possible for you. The following should be mentioned: high blood pressure, history of drug abuse, hyperthyroidism, heart disease, diabetes, arteriosclerosis, glaucoma and some other ones.